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November 21, 2006; 103 (47)

Cover illustration

Cover image expansion

Cover image: The 24 human chromosomes showing all of the SVA mobile element-mediated sequence transduction events mapped to individual chromosomes (shown as light lines and dots). SVA is a composite retrotransposon named for its main components: SINE, VNTR, and Alu. Gene duplication and transduction events for the acyl-malonyl condensing enzyme (AMAC) gene are shown as red lines; AMAC is an enzyme involved in fatty acid synthesis. See the article by Xing et al. on pages 17608–17613. Image courtesy of Bang Wong (ClearScience, Cambridge, MA), Jinchuan Xing, and Mark A. Batzer; the single copies of each chromosome are adapted from a human male karyotype image (Copyright 2003, Howard Hughes Medical Institute).

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