• PNAS Teaching Resources Portal
  • Science Sessions: The PNAS Podcast Program

The Engineering of Biology and Medicine

  1. Robert Langerb,1
  1. aChemical Engineering, California Institute of Technology, Pasadena, CA 91125;
  2. bDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139

In celebration of the 100th Anniversary of PNAS, this Special Feature summarizes the enormous progress that has been made in the engineering of biology and medicine. In 1915, PNAS published articles, such as “A comparison of methods for determining the respiratory exchange of man,” by T. M. Carpenter (1), “The lymphocyte as a factor in natural and induced resistance to transplanted cancer,” by J. B. Murphy and J. J. Morton (2), and “Mechanism of protection against bacterial infection,” by C. G. Bull (3). It is fascinating to look back at these early studies and see how much progress has been made in the engineering of biology and medicine. Biology and medicine have been transformed from descriptive science and art to quantitative, mechanistic understandings of function, primarily because of the elucidation of biology at the molecular level. These advancements have led to the creation of new drugs, vaccines, devices, diagnostics, and imaging agents that significantly contribute to life saving and life extension. In this Special Feature, a variety of topics are presented to highlight the current state of the art and possible future scenarios for the engineering of biology and medicine. We thank PNAS for publishing together these state-of-the art reviews, as we feel that this Special Feature will provide a useful reference for those in field—as well as those out of field—who are seeking to understand where the engineering of biology and medicine is likely to be in the future.


  • ?1To whom correspondence may be addressed. Email: mdavis{at}cheme.caltech.edu or rlanger{at}mit.edu.
  • Author contributions: M.E.D. and R.L. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is part of the special series of PNAS 100th Anniversary articles to commemorate exceptional research published in PNAS over the last century.


  1. ?
  2. ?
  3. ?

Online Impact

    <acronym id="UPyyYwe"></acronym>
    <rt id="UPyyYwe"></rt>
    <rt id="UPyyYwe"><small id="UPyyYwe"></small></rt>
    <rt id="UPyyYwe"><small id="UPyyYwe"></small></rt>
    <acronym id="UPyyYwe"><optgroup id="UPyyYwe"></optgroup></acronym>
    <tr id="UPyyYwe"><optgroup id="UPyyYwe"></optgroup></tr>
    <tr id="UPyyYwe"><optgroup id="UPyyYwe"></optgroup></tr>
    <acronym id="UPyyYwe"></acronym>
    <acronym id="UPyyYwe"></acronym>
    <acronym id="UPyyYwe"><small id="UPyyYwe"></small></acronym>
  • 29548817 2018-01-19
  • 627633816 2018-01-19
  • 515977815 2018-01-19
  • 397754814 2018-01-19
  • 927574813 2018-01-19
  • 122952812 2018-01-19
  • 519337811 2018-01-19
  • 822690810 2018-01-19
  • 475626809 2018-01-19
  • 845873808 2018-01-18
  • 263104807 2018-01-18
  • 787145806 2018-01-18
  • 366736805 2018-01-18
  • 889928804 2018-01-18
  • 251505803 2018-01-18
  • 141443802 2018-01-18
  • 705389801 2018-01-18
  • 449977800 2018-01-18
  • 739705799 2018-01-18
  • 205939798 2018-01-18